Hydroxypropyl Methyl Cellulose (HPMC), ti a tun mọ nipasẹ orukọ iṣowo hypromellose, jẹ polima sintetiki ti o wa lati cellulose adayeba. Awọn jc orisun ti cellulose fun isejade ti HPMC ni ojo melo igi ti ko nira tabi owu. Ilana iṣelọpọ pẹlu kemikali iyipada cellulose nipasẹ etherification, ṣafihan hydroxypropyl ati awọn ẹgbẹ methyl sori ẹhin cellulose.

Ṣiṣejade ti HPMC ni awọn igbesẹ pupọ:

1. Iyọkuro Cellulose:
   • A gba cellulose lati awọn orisun ọgbin, nipataki igi ti ko nira tabi owu. Awọn cellulose ti wa ni jade ki o si wẹ lati dagba cellulose pulp.
2. Alkalization:
   • A ṣe itọju pulp cellulose pẹlu ojutu ipilẹ, nigbagbogbo sodium hydroxide (NaOH), lati mu awọn ẹgbẹ hydroxyl ṣiṣẹ lori pq cellulose.
3. Etherification:
   • Etherification jẹ igbesẹ bọtini ni iṣelọpọ ti HPMC. Cellulose alkalized ti wa ni idahun pẹlu propylene oxide (fun awọn ẹgbẹ hydroxypropyl) ati methyl kiloraidi (fun awọn ẹgbẹ methyl) lati ṣafihan awọn ẹgbẹ ether wọnyi sori ẹhin cellulose.
4. Idaduro ati fifọ:
   • Abajade cellulose ti a ṣe atunṣe, eyiti o jẹ Hydroxypropyl Methyl Cellulose ni bayi, gba ilana imukuro lati yọ eyikeyi alkali ti o ku kuro. Lẹhinna a fọ ​​rẹ daradara lati yọkuro awọn aimọ ati awọn ọja-ọja.
5. Gbigbe ati Milling:
   • A ti gbẹ cellulose ti a ṣe atunṣe lati yọ ọrinrin ti o pọju kuro ati lẹhinna a lọ sinu erupẹ ti o dara. Iwọn patiku le jẹ iṣakoso da lori ohun elo ti a pinnu.

Abajade ọja HPMC jẹ funfun tabi pa-funfun lulú pẹlu awọn iwọn oriṣiriṣi ti hydroxypropyl ati aropo methyl. Awọn ohun-ini kan pato ti HPMC, gẹgẹbi solubility rẹ, iki, ati awọn abuda iṣẹ ṣiṣe miiran, da lori iwọn aropo ati ilana iṣelọpọ.

O ṣe pataki lati ṣe akiyesi pe HPMC jẹ polima-sintetiki ologbele, ati lakoko ti o jẹ yo lati cellulose adayeba, o ṣe awọn iyipada kemikali pataki lakoko ilana iṣelọpọ lati ṣaṣeyọri awọn ohun-ini ti o fẹ fun ọpọlọpọ awọn ohun elo ile-iṣẹ.