Pharmaceutical ite HPMC
Pharmaceutical ite HPMCHydroxypropyl methylcellulose jẹ funfun tabi wara funfun, olfato, aini itọwo, erupẹ fibrous tabi granule, pipadanu iwuwo lori gbigbe ko kọja 10%, tiotuka ninu omi tutu ṣugbọn kii ṣe omi gbona, laiyara ninu omi gbona Wiwu, peptization, ati ṣiṣe ojutu colloidal viscous , eyi ti o di ojutu nigbati o tutu, o si di gel nigbati o ba gbona.HPMC ko ṣee ṣe ni ethanol, chloroform ati ether.O ti wa ni tiotuka ni a adalu epo kẹmika ati methyl kiloraidi.O tun jẹ tiotuka ninu epo ti o dapọ ti acetone, methyl chloride ati isopropanol ati diẹ ninu awọn olomi Organic miiran.Ojutu olomi rẹ le fi aaye gba iyọ (ojutu colloidal rẹ ko ni run nipasẹ iyọ), ati pH ti 1% ojutu olomi jẹ 6-8.Ilana molikula ti HPMC jẹ C8H15O8- (C10H18O6) -C815O, ati iwọn molikula ibatan jẹ nipa 86,000.
Kemikali sipesifikesonu
| Pharmaceutical HPMC Sipesifikesonu | HPMC60E( 2910) | HPMC65F( 2906) | HPMC75K( 2208) |
| Iwọn jeli (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Solusan) | 3, 5, 6, 15, 50,100,400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Iwọn ọja:
| Pharmaceutical HPMC Sipesifikesonu | HPMC60E( 2910) | HPMC65F( 2906) | HPMC75K( 2208) |
| Iwọn jeli (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Solusan) | 3, 5, 6, 15, 50,100,400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Ohun elo
| PharmaAwọn afikunOhun elo | Pharmaceutical Grade HPMC | Iwọn lilo |
| Olopobobo Laxative | 75K4000,75K100000 | 3-30% |
| Awọn ipara, gels | 60E4000,75K4000 | 1-5% |
| Igbaradi Ophthalmic | 60E4000 | 01.-0.5% |
| Awọn igbaradi Awọn silẹ Oju | 60E4000 | 0.1-0.5% |
| Aṣoju idaduro | 60E4000, 75K4000 | 1-2% |
| Antacids | 60E4000, 75K4000 | 1-2% |
| Awọn tabulẹti Asopọmọra | 60E5, 60E15 | 0.5-5% |
| Adehun tutu granulation | 60E5, 60E15 | 2-6% |
| Tablet Coatings | 60E5, 60E15 | 0.5-5% |
| Matrix itusilẹ ti iṣakoso | 75K100000,75K15000 | 20-55% |
Awọn ẹya ara ẹrọ ati awọn anfani:
HPMC ni o ni o tayọ omi solubility ni tutu omi.O le ti wa ni tituka sinu kan sihin ojutu pẹlu kekere kan saropo ni tutu omi.Ni ilodi si, o jẹ ipilẹ insoluble ninu omi gbona ju 60 lọ℃ati ki o le nikan wú.O jẹ ether cellulose ti kii-ionic.Ojutu rẹ ko ni idiyele ionic, ko ṣe ajọṣepọ pẹlu awọn iyọ irin tabi awọn agbo ogun Organic ionic, ati pe ko ṣe pẹlu awọn ohun elo aise miiran lakoko ilana igbaradi;o ni o ni agbara egboogi-ifamọ, ati bi awọn ìyí ti aropo ninu awọn molikula besoke, awọn oniwe-O jẹ diẹ sooro si Ẹhun ati diẹ idurosinsin;o tun jẹ inert ti iṣelọpọ agbara.Gẹgẹbi olutọpa elegbogi, ko jẹ metabolized tabi gbigba.Nitorina, ko pese ooru ni awọn oogun ati awọn ounjẹ.O jẹ kalori-kekere, laisi iyọ, ati ti kii ṣe iyo-ọfẹ fun awọn alamọgbẹ.Awọn oogun ti ara korira ati awọn ounjẹ ni iwulo alailẹgbẹ;o jẹ iduroṣinṣin si awọn acids ati alkalis, ṣugbọn ti iye PH ba kọja 2 ~ 11 ati pe o ni ipa nipasẹ awọn iwọn otutu ti o ga tabi ni akoko ipamọ to gun, iki rẹ yoo dinku;Ojutu olomi rẹ le pese iṣẹ ṣiṣe dada, ti n ṣafihan ẹdọfu dada iwọntunwọnsi ati awọn iye ẹdọfu interfacial;o ni emulsification ti o munadoko ni awọn ọna ṣiṣe-meji, le ṣee lo bi amuduro ti o munadoko ati colloid aabo;awọn oniwe-olomi ojutu ni o ni o tayọ film-lara-ini, ati ki o jẹ a tabulẹti ati egbogi A ti o dara ti a bo ohun elo.Aṣọ fiimu ti a ṣẹda nipasẹ rẹ ni awọn anfani ti aila-awọ ati lile.Ṣafikun glycerin tun le ṣe ilọsiwaju ṣiṣu rẹ.
Iṣakojọpọ
TIṣakojọpọ boṣewa jẹ 25kg /Okunilu
20'FCL: 9 pupọ pẹlu palletized;10 pupọ unpalletized.
40'FCL:18pupọ pẹlu palletized;20pupọ unpalletized.
Ibi ipamọ:
Tọju rẹ ni itura, aye gbigbẹ ni isalẹ 30 ° C ati aabo lodi si ọriniinitutu ati titẹ, nitori awọn ẹru jẹ thermoplastic, akoko ipamọ ko yẹ ki o kọja oṣu 36.
Awọn akọsilẹ ailewu:
Awọn data ti o wa loke wa ni ibamu pẹlu imọ wa, ṣugbọn maṣe gba awọn alabara laaye ni iṣọra ṣayẹwo gbogbo rẹ lẹsẹkẹsẹ lori gbigba.Lati yago fun agbekalẹ oriṣiriṣi ati awọn ohun elo aise, jọwọ ṣe idanwo diẹ sii ṣaaju lilo rẹ.
Akoko ifiweranṣẹ: Jan-01-2024